c
2
12
18
28
12
12
1a
14
e
12
16
a
a
2
2
a
20
32
1a
2a
19
Faculty
61 16
19
1
49
2
2
1a
32
34
1b
1d
18
39
51
1d
2 29
1d
25
Kimberly M Christian, Ph.D.
88
51
Research Assistant Professor of Neuroscience
7
63
Department: Neuroscience
4
1
23
1f
Graduate Group Affiliations
8
a
b
1d
46
Contact information
49
4
3
3
3
2
4
b
1f
49
Perelman School of Medicine
22 Department of Neuroscience
20 415 Curie Blvd, CRB 105A
47 1st Floor Clinical Research Building
Philadelphia, PA 19104
26
22 Department of Neuroscience
20 415 Curie Blvd, CRB 105A
47 1st Floor Clinical Research Building
Philadelphia, PA 19104
2e
Office: 215-573-2147
30
9f
12
30
13
Education:
21 9 B.A. 17 (Philosophy) c
3d University of California at Berkeley, 1993.
21 a Ph.D. 19 (Neuroscience) c
3a University of Southern California, 2004.
c
3
3
3
3
92
Permanent link21 9 B.A. 17 (Philosophy) c
3d University of California at Berkeley, 1993.
21 a Ph.D. 19 (Neuroscience) c
3a University of Southern California, 2004.
c
2 29
21
1e
1d
24
2b
29
27
23
1a2 Guo, Z., Su, Y., Huang, W. K., Yao, X. S., Hong, Y., Gordin, A., Nguyen, H. N., Wen, Z., Ringeling, F. R., Chen, G., Li, S., Lu, L., Xia, M., Zheng, W., Sawa, A., Chen, G., Christian, K. M., Song, H., Ming, G. L.: GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders. bioRxiv 2024.
1c4 LaNoce, E., Zhang, D. Y., Garcia-Epelboim, A., Su, Y., Sun, Y., Alepa, G., Angelucci, A. R., Akay-Espinoza, C., Jordan-Sciutto, K. L., Song, H., Ming, G. L., Christian, K. M.: Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development. Front Mol Neurosci 17: 1459877, 2024.
10a Kim SH, GoodSmith D, Temme SJ, Moriya F, Ming GL, Christian KM, Song H, Knierim JJ.: Global remapping in granule cells and mossy cells of the mouse dentate gyrus. Cell Rep 42: 112334, Apr 2023.
cb Garcia-Epelboim A, Christian KM.: Modeling neuro-immune interactions using human pluripotent stem cells. Curr Opin Neurobiol 2023.
d9 LaNoce E, Dumeng-Rodriguez J, Christian KM. : Using 2D and 3D pluripotent stem cell models to study neurotropic viruses. Front Virol. July 2022.
105 GoodSmith D, Kim SH, Puliyadi V, Ming GL, Song H, Knierim JJ, Christian KM.: Flexible encoding of objects and space in single cells of the dentate gyrus. Curr Biol 32: 1088-1101, Mar 2022.
ca Fan W, Christian KM, Song H, Ming GL.: Applications of Brain Organoids for Infectious Diseases. J Mol Biol 434: 167243, Feb 2022.
1ab Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, Yoon KJ, Song H, Ming GL.: CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biol Psychiatry May 2021.
179 Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL.: Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol Psychiatry 26: 1346-1360, Apr 2021.
2c
7
1d
1f
Selected Publications
1aa Sun, Y., Wang, X., Zhang, Z., Park, K. H., Wu, Y., Dong, W., Zhang, D. Y., Fu, Y., Zhang, F., Binder, Z. A., Ling-Lin Pai, E., Nasrallah, M. P., Christian, K. M., O'Rourke, D. M., Toni, N., Ming, G. L., Song, H.: Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model. Stem Cell Reports 20(7): 102534, 2025.1a2 Guo, Z., Su, Y., Huang, W. K., Yao, X. S., Hong, Y., Gordin, A., Nguyen, H. N., Wen, Z., Ringeling, F. R., Chen, G., Li, S., Lu, L., Xia, M., Zheng, W., Sawa, A., Chen, G., Christian, K. M., Song, H., Ming, G. L.: GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders. bioRxiv 2024.
1c4 LaNoce, E., Zhang, D. Y., Garcia-Epelboim, A., Su, Y., Sun, Y., Alepa, G., Angelucci, A. R., Akay-Espinoza, C., Jordan-Sciutto, K. L., Song, H., Ming, G. L., Christian, K. M.: Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development. Front Mol Neurosci 17: 1459877, 2024.
10a Kim SH, GoodSmith D, Temme SJ, Moriya F, Ming GL, Christian KM, Song H, Knierim JJ.: Global remapping in granule cells and mossy cells of the mouse dentate gyrus. Cell Rep 42: 112334, Apr 2023.
cb Garcia-Epelboim A, Christian KM.: Modeling neuro-immune interactions using human pluripotent stem cells. Curr Opin Neurobiol 2023.
d9 LaNoce E, Dumeng-Rodriguez J, Christian KM. : Using 2D and 3D pluripotent stem cell models to study neurotropic viruses. Front Virol. July 2022.
105 GoodSmith D, Kim SH, Puliyadi V, Ming GL, Song H, Knierim JJ, Christian KM.: Flexible encoding of objects and space in single cells of the dentate gyrus. Curr Biol 32: 1088-1101, Mar 2022.
ca Fan W, Christian KM, Song H, Ming GL.: Applications of Brain Organoids for Infectious Diseases. J Mol Biol 434: 167243, Feb 2022.
1ab Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, Yoon KJ, Song H, Ming GL.: CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biol Psychiatry May 2021.
179 Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL.: Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol Psychiatry 26: 1346-1360, Apr 2021.
2c
4d
22
22
7
10
a
a
2
2
19
18
10
22
10
11
c
5b © The Trustees of the University of Pennsylvania | Site best viewed a in a supported browser. | Site Design: 57 PMACS Web Team. 3 22
10