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Thomas H. Leung, M.D., Ph.D.
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Herman Beerman, MD II Professor in Dermatology
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Department: Dermatology
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Graduate Group Affiliations
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- Cell and Molecular Biology 5c
- Immunology e
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Contact information
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421 Curie Boulevard
56 1001 Biomedical Research Building II/III, Room 1006
Philadelphia, PA 19104
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56 1001 Biomedical Research Building II/III, Room 1006
Philadelphia, PA 19104
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Email:
thl@pennmedicine.upenn.edu
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thl@pennmedicine.upenn.edu
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Education:
21 9 B.S. 20 (Biological Sciences) c
3a Stanford University, Stanford, CA, 1998.
21 a Ph.D. 14 (Biology) c
49 California Institute of Technology, Pasadena, CA, 2005.
21 9 M.D. 15 (Medicine) c
41 UCLA School of Medicine, Los Angeles, CA, 2007.
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Permanent link21 9 B.S. 20 (Biological Sciences) c
3a Stanford University, Stanford, CA, 1998.
21 a Ph.D. 14 (Biology) c
49 California Institute of Technology, Pasadena, CA, 2005.
21 9 M.D. 15 (Medicine) c
41 UCLA School of Medicine, Los Angeles, CA, 2007.
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141 Huang J., Sati S., Ahart O., Rapp-Reyes E., Zhou L., Micheletti R.G., James W, Rosenbach M, and Leung T.H. : SAA1/FPR2 signaling between keratinocytes and neutrophils sustains chronic inflammation in Sweet syndrome. J Clin Invest 135(20), Aug 2025.
cb Zhou L. and Leung T.H.: Detection by single-cell RNA-sequencing of virally-mediated skin diseases. JID Innovations 5(3), Jan 2025.
14c Huang J., Sati S., Murphy C., Spencer C.A., Rapp E., Prouty S., Korte S., Ahart O., Sheng E., Jones P., Kersh A., Leung D., and Leung T.H. : Granulocyte-colony stimulating factor promotes scarless tissue regeneration. Cell Reports 43(10): 114742, Sep 21 2024.
162 Chen B., He B., Tucker A.M., Biluck I., Leung T.H., Schaer T.P., and Yang S.: An Environmentally Stable, Biocompatible, and Multilayered Wound Dressing Film with Reversible and Strong Adhesion. Advanced Healthcare Materials Page: e2400827, Sep 12 2024 Notes: Online ahead of print.
15b Sati S, Jones P, Kersh A, Murphy C, Hedberg ML, Huang J, Jain V, Gregory SG, Leung DH, Rosenbach M., and Leung T.H. : Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granuloma diseases. J Clin Invest 134(17): e179711, Sep 3 2024.
102 Kersh A., Sati S., Murphy C., Ahart O., and Leung T.H. : CXCL9, CXCL10, and CCL19 synergistically recruit T-lymphocytes to skin in lichen planus. JCI Insight Page: e179899, Aug 27 2024.
17d Bhattacharya S., Sheng E., Murphy C., Wei J., Kersh A., Nelson C.A., Bryer J.S., Ashchyan H.A., Steele K., Forrestel A., Seykora J.T., Micheletti R.G., James W.D., Rosenbach M., and Leung T.H. : Treatment of Sweet Syndrome Guided by Molecular Identification of PIK3R1 mutation. JCI 133(1): e162137, Jan 2023.
143 Sati S., Jones P., Kim H.S., Zhou L.A., Rapp-Reyes E., and Leung T.H. : HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLOS Genetics 18(3): e1010121, Mar 23 2022 Notes: doi: 10.1371/journal.pgen.1010121.
111 Weiss E.H., Ko C.J., Leung T.H., Micheletti R.G., Mostaghimi A., Ramachandran S.M., Rosenbach M., Nelson C.A.: Neutrophilic Dermatoses: a Clinical Update. Curr Dermatol Rep 11(2): 89-102, Mar 16 2022.
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Selected Publications
104 Rapp E., Pang J., Saeednia B., Prouty S.M., Reilly C.A., and Leung T.H.: Carnosic acid in topical rosemary extract enhances skin repair via TRPA1 activation. JCI Insight 10(23), Oct 2025.141 Huang J., Sati S., Ahart O., Rapp-Reyes E., Zhou L., Micheletti R.G., James W, Rosenbach M, and Leung T.H. : SAA1/FPR2 signaling between keratinocytes and neutrophils sustains chronic inflammation in Sweet syndrome. J Clin Invest 135(20), Aug 2025.
cb Zhou L. and Leung T.H.: Detection by single-cell RNA-sequencing of virally-mediated skin diseases. JID Innovations 5(3), Jan 2025.
14c Huang J., Sati S., Murphy C., Spencer C.A., Rapp E., Prouty S., Korte S., Ahart O., Sheng E., Jones P., Kersh A., Leung D., and Leung T.H. : Granulocyte-colony stimulating factor promotes scarless tissue regeneration. Cell Reports 43(10): 114742, Sep 21 2024.
162 Chen B., He B., Tucker A.M., Biluck I., Leung T.H., Schaer T.P., and Yang S.: An Environmentally Stable, Biocompatible, and Multilayered Wound Dressing Film with Reversible and Strong Adhesion. Advanced Healthcare Materials Page: e2400827, Sep 12 2024 Notes: Online ahead of print.
15b Sati S, Jones P, Kersh A, Murphy C, Hedberg ML, Huang J, Jain V, Gregory SG, Leung DH, Rosenbach M., and Leung T.H. : Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granuloma diseases. J Clin Invest 134(17): e179711, Sep 3 2024.
102 Kersh A., Sati S., Murphy C., Ahart O., and Leung T.H. : CXCL9, CXCL10, and CCL19 synergistically recruit T-lymphocytes to skin in lichen planus. JCI Insight Page: e179899, Aug 27 2024.
17d Bhattacharya S., Sheng E., Murphy C., Wei J., Kersh A., Nelson C.A., Bryer J.S., Ashchyan H.A., Steele K., Forrestel A., Seykora J.T., Micheletti R.G., James W.D., Rosenbach M., and Leung T.H. : Treatment of Sweet Syndrome Guided by Molecular Identification of PIK3R1 mutation. JCI 133(1): e162137, Jan 2023.
143 Sati S., Jones P., Kim H.S., Zhou L.A., Rapp-Reyes E., and Leung T.H. : HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLOS Genetics 18(3): e1010121, Mar 23 2022 Notes: doi: 10.1371/journal.pgen.1010121.
111 Weiss E.H., Ko C.J., Leung T.H., Micheletti R.G., Mostaghimi A., Ramachandran S.M., Rosenbach M., Nelson C.A.: Neutrophilic Dermatoses: a Clinical Update. Curr Dermatol Rep 11(2): 89-102, Mar 16 2022.
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