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Katherine Uyhazi, MD, PhD
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Assistant Professor of Ophthalmology
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Department: Ophthalmology
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Graduate Group Affiliations
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Contact information
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Stellar Chance Laboratories, Rm 313A
31 422 Curie Blvd
Philadelphia, PA 19104
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31 422 Curie Blvd
Philadelphia, PA 19104
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Office: (215) 662-8816
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Education:
21 8 B.S 14 (Biology) c
32 The College of New Jersey, 2005.
21 f M.D/Ph.D. 19 (Cell Biology) c
30 Yale School of Medicine, 2013.
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Permanent link21 8 B.S 14 (Biology) c
32 The College of New Jersey, 2005.
21 f M.D/Ph.D. 19 (Cell Biology) c
30 Yale School of Medicine, 2013.
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1c Retinitis pigmentosa
19 Stargardt disease
1a Cone rod dystrophy
22 Leber congenital amaurosis
16 Gyrate atrophy
21 Electroretinography (ERG)
16 Genetic testing
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19 Stem cell therapy
1c Retinal regeneration
21 Photoreceptor development
1d Subretinal injections
2e Induced Pluripotent Stem Cells (iPSCs)
24 Murine models of eye disease
2d Single cell RNA sequencing (scRNAseq)
18 Retinal histology
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Description of Clinical Expertise
30 Inherited retinal degenerations1c Retinitis pigmentosa
19 Stargardt disease
1a Cone rod dystrophy
22 Leber congenital amaurosis
16 Gyrate atrophy
21 Electroretinography (ERG)
16 Genetic testing
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Description of Research Expertise
25 Retinal gene therapy19 Stem cell therapy
1c Retinal regeneration
21 Photoreceptor development
1d Subretinal injections
2e Induced Pluripotent Stem Cells (iPSCs)
24 Murine models of eye disease
2d Single cell RNA sequencing (scRNAseq)
18 Retinal histology
e 29
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20d Aleman TS, Uyhazi KE, Roman AJ, Weber ML, O'Neil EC, Swider M, Sumaroka A, Maguire KH, Aleman EM, Santos AJ, Kim RJ, Parchinski KM, Billek A, Fradin M, Chung W, Margaritis P, Sun J, Scoles DH, Wu V, Garafalo AV, Jayagopal A, Yerxa B, Tuller S, Maguire AM, Bennett J, Cideciyan AV.: Recovery of cone-mediated vision in Lebercilin associated retinal ciliopathy after gene therapy: One-year results of a phase I/II trial. Mol Ther 33: 4784-4798, Oct 2025.
cb Pham K, Uyhazi KE.: Retinal Findings in Kjellin Syndrome. Ophthalmology Aug 2025 Notes: In press; published online ahead of print.
117 Wilder RJ, An AF, Bell BA, Fossett G, Wojciechowski AM, Shpylchak I, Uyhazi KE.: Intraretinal variation in disease severity in the Oat(rhg) mouse model of gyrate atrophy. Exp Eye Res 255: 110382, June 2025.
167 Yano JJ, Wei Z, Bell BA, Uyhazi KE: Lineage Tracing of Photoreceptor Precursor Cell Subpopulations During Murine Retinal Development. 20th International Congress of Developmental Biology / Society for Developmental Biology 84th Annual Meeting (San Juan, Puerto Rico) 2025 Notes: Poster.
149 Yano JJ, Wei Z, Bell BA, Uyhazi KE.: Lineage Tracing of Photoreceptor Precursor Cell Subpopulations During Murine Retinal Development. 2025 Mid-Atlantic Society for Developmental Biology (SDB) Regional Meeting (Richmond, VA). 2025 Notes: Oral presentation.
248 Aleman TS, Cideciyan AV, Uyhazi KE, Weber ML, Roman AJ, Swider M, Sumaroka A, Maguire KH, Aleman EM, O'Neil EC, Santos A, Kim RJ, Parchinski KM, Fradin M, Chung W, Margaritis P, Sun J, Scoles DH, Wu V, Garafalo AV, Jayagopal A, Yerxa B, Tuller S, Maguire AM, Bennett J.: Recovery of Cone-Mediated Vision in a Severe Ciliopathy after Gene Augmentation One Year Results of a Phase I/II Trial for LCA5-LCA. Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting (Salt Lake City, UT) 2025.
11e Passino R, Bell B, Uyhazi KE: Microglia Inhibition Improves Gene Therapy in a Mouse Model of Photoreceptor Degeneration. 152nd Anniversary Meeting of the Scheie Eye Institute (Philadelphia, PA) 2025 Notes: Poster.
12e Yano JJ, Wei Z, Uyhazi KE: Lineage Tracing Photoreceptor Precursor Cells During Murine Retinal Development. Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting (Salt Lake City, UT) 2025 Notes: Poster.
112 Yano JJ, Wei Z, Uyhazi KE: Lineage Tracing Photoreceptor Precursor Cells During Murine Retinal Development. 152nd Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) 2025 Notes: Poster.
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Selected Publications
300 Oertel FC, Cabrera Debuc D, Calabresi PA, Chen M, Cordano C, Dietrich M, Feltgen N, Gramlich O, Green AJ, Groh J, Huang SC, Knier B, Korn T, Leocani L, Loewenstein A, van Oterendorp C, Peto T, Schippling S, Schmetterer L, Schmitz-Valckenberg S, Seeliger MW, Shindler KS, Schuman JS, Sindi M, Tufail A, Wang JK, Wolf S, You Y, Zinkernagel M, Lagrèze W, Albrecht P; IMSVISUAL consortium.: APOSTEL-R Recommendations for Reporting Retinal Optical Coherence Tomography Studies in Rodents. Neurol Neuroimmunol Neuroinflamm. Published online ahead of print. In press, Nov 2025 Notes: Listed in Co-investigator Appendix for participating in questionnaires regarding retinal OCT measurements in rodents.20d Aleman TS, Uyhazi KE, Roman AJ, Weber ML, O'Neil EC, Swider M, Sumaroka A, Maguire KH, Aleman EM, Santos AJ, Kim RJ, Parchinski KM, Billek A, Fradin M, Chung W, Margaritis P, Sun J, Scoles DH, Wu V, Garafalo AV, Jayagopal A, Yerxa B, Tuller S, Maguire AM, Bennett J, Cideciyan AV.: Recovery of cone-mediated vision in Lebercilin associated retinal ciliopathy after gene therapy: One-year results of a phase I/II trial. Mol Ther 33: 4784-4798, Oct 2025.
cb Pham K, Uyhazi KE.: Retinal Findings in Kjellin Syndrome. Ophthalmology Aug 2025 Notes: In press; published online ahead of print.
117 Wilder RJ, An AF, Bell BA, Fossett G, Wojciechowski AM, Shpylchak I, Uyhazi KE.: Intraretinal variation in disease severity in the Oat(rhg) mouse model of gyrate atrophy. Exp Eye Res 255: 110382, June 2025.
167 Yano JJ, Wei Z, Bell BA, Uyhazi KE: Lineage Tracing of Photoreceptor Precursor Cell Subpopulations During Murine Retinal Development. 20th International Congress of Developmental Biology / Society for Developmental Biology 84th Annual Meeting (San Juan, Puerto Rico) 2025 Notes: Poster.
149 Yano JJ, Wei Z, Bell BA, Uyhazi KE.: Lineage Tracing of Photoreceptor Precursor Cell Subpopulations During Murine Retinal Development. 2025 Mid-Atlantic Society for Developmental Biology (SDB) Regional Meeting (Richmond, VA). 2025 Notes: Oral presentation.
248 Aleman TS, Cideciyan AV, Uyhazi KE, Weber ML, Roman AJ, Swider M, Sumaroka A, Maguire KH, Aleman EM, O'Neil EC, Santos A, Kim RJ, Parchinski KM, Fradin M, Chung W, Margaritis P, Sun J, Scoles DH, Wu V, Garafalo AV, Jayagopal A, Yerxa B, Tuller S, Maguire AM, Bennett J.: Recovery of Cone-Mediated Vision in a Severe Ciliopathy after Gene Augmentation One Year Results of a Phase I/II Trial for LCA5-LCA. Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting (Salt Lake City, UT) 2025.
11e Passino R, Bell B, Uyhazi KE: Microglia Inhibition Improves Gene Therapy in a Mouse Model of Photoreceptor Degeneration. 152nd Anniversary Meeting of the Scheie Eye Institute (Philadelphia, PA) 2025 Notes: Poster.
12e Yano JJ, Wei Z, Uyhazi KE: Lineage Tracing Photoreceptor Precursor Cells During Murine Retinal Development. Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting (Salt Lake City, UT) 2025 Notes: Poster.
112 Yano JJ, Wei Z, Uyhazi KE: Lineage Tracing Photoreceptor Precursor Cells During Murine Retinal Development. 152nd Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) 2025 Notes: Poster.
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