Faculty

Todd J. Kilbaugh, MD

Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia

Department: Anesthesiology and Critical Care

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104

Office: 267-426-7131
Fax: 215-590-4327

Email:
kilbaugh@chop.edu

Education:
BS (Biology)
Wake Forest University, 1994.
MD (Medicine)
Medical University of South Carolina, 1999.

Links
Injury Biomechanics Lab. University of Pennsylvania, Department of Bioengineering

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Silva LEV, Gaudio HA, Padmanabhan V, Forti RM, Shi L, Mason M, Sueishi T, Kirschen MP, Baker WB, Kilbaugh TJ, Morgan RW, Tsui FR, Ko TS.: Machine Learning-Based Return of Spontaneous Circulation Prediction During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest: Effect of Data Resolution and Multimodal Physiological Waveforms. Crit Care Med 54: 257-269, Feb 2026.

McManus MJ, Zhu Y, Alves C, Kohli N, Prada-Dacasa P, Sanchez-Benito L, Sanz E, Yee I, Robinson L, Sheldon M, McHugh WJ, Ranganathan A, Meng J, Duncan N, Grönberg A, Wallace DC, Piel S, Karlsson M, Moss SJ, Webster L, Hansson MJ, Elmér E, Ehinger JK, Quintana A, Kilbaugh TJ.: The succinate prodrug NV354 prevents brain lesions and late-stage motor dysfunction in mitochondrial complex I deficiency. iScience 29: 114717, Jan 2026.

Lewis A, Forti RM, Ko TS, Elmér E, McManus MJ, Yodh AG, Kilbaugh TJ, Baker WB.: Optical and Microdialysis Monitoring of Succinate Prodrug Treatment in a Rotenone-Induced Model of Mitochondrial Dysfunction in Swine. Metabolites 16: 65, Jan 2026.

Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators.: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation 2026.

Shin SS, Browne KD, Viaene AN, Keim G, Han DJ, Degani R, Mazandi V, Morton S, Starr J, Weeks K, Widmann N, Hobson L, Gaudio H, Ko TS, Menezes-Forti R, Jang DH, Cullen DK, Kilbaugh TJ, Kao SH.: Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs. J Neurotrauma Dec 2025.

Loaec M, Keim G, Graham K, Kienzle MF, O'Halloran A, Shepard LN, Mehta S, Sawhney S, Donoghue M, Cooper K, Kilbaugh TJ, Nadkarni V, Topjian AA, Berg RA, Sutton RM, Morgan RW.: Comparison of vasopressin to epinephrine during pediatric in-hospital cardiac arrest: survival and physiologic responsiveness. Pediatr Res Oct 2025.

Smood B, Aronowitz DI, Noji M, Shoffler C, Abbasian D, Petucci C, Fiock KL, Hefti M, Degani R, Melchior RW, Catalano M, Arany Z, Yudkoff M, Gaynor JW, Kilbaugh T, Mavroudis CD.: Branched-Chain Amino Acids Accumulate and Glutamate Decreases in Cerebral Interstitial Fluid Following Cardiopulmonary Bypass in Neonatal Swine. Eur J Cardiothorac Surg 67: ezaf311, Oct 2025.

Morgan RW, Reeder RW, Carcillo JA, Carpenter TC, Fitzgerald JC, Graham K, Kilbaugh TJ, Meert KL, Nadkarni VM, Palmer CA, Sharron MP, Weiss SL, Wolfe HA, Ahmed T, Bell MJ, Bishop R, Burns C, Diddle JW, Fink EL, Franzon D, Frazier AH, Friess SH, Hehir DA, Horvat CM, Huard LL, Maa T, McQuillen PS, Mourani PM, Naim MY, Pollack MM, Sapru A, Srivastava N, Yates AR, Berg RA, Sutton RM; ICU-Resuscitation Project (ICU-RESUS) Investigators and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Investigators: Outcomes, Characteristics, and Physiology of In-Hospital Cardiac Arrest in Children With Sepsis. Critical Care Medicine 53(8): e1529-e1541, August 2025.

Siems A, Naim MY, Berg RA, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Harding ML, Hehir DA, Horvat CM, Huard LL MD, Kilbaugh TJ, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Notterman D, Pollack MM, Qunibi DW, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Morgan RW, Sutton RM.: Association of Early Epinephrine with Hemodynamics and Outcome in Pediatric In-Hospital Cardiac Arrest: A Secondary Analysis of a Multi-center, Cluster-randomized Clinical Trial (ICU-RESUS). Ann Am Thorac Soc Jun 2025.

Mazandi VM, Boggs K, Senthil K, Gabriel ED, Kumar N, Glau C, Himebauch AS, Kim CT, Kilbaugh TJ, Lang SS, Conlon T, Huh JW.: Association of left ventricular systolic dysfunction with outcome following pediatric traumatic brain injury. J Neurosurg Pediatr May 2025.